| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-05 | Tennessee St | 219 | 39.19 | 16 - 10 |
| 2021-09-11 | @ Southern Miss | 137 | 8.14 | 0 - 37 |
| 2021-09-18 | @ Houston | 71 | 1.36 | 0 - 45 |
| 2021-09-25 | Prairie View | 210 | 34.37 | 34 - 31 |
| 2021-10-02 | Alabama A&M | 202 | 35.14 | 37 - 28 |
| 2021-10-09 | @ Alcorn St | 169 | 18.52 | 20 - 24 |
| 2021-10-16 | TX Southern | 246 | 76.56 | 34 - 20 |
| 2021-10-30 | @ Florida A&M | 189 | 27.15 | 3 - 26 |
| 2021-11-06 | @ Ark Pine Bluff | 252 | 69.34 | 26 - 33 |
| 2021-11-13 | Bethune-Cookman | 225 | 54.42 | 14 - 31 |
| 2021-11-27 | Southern Univ | 216 | 33.41 | 0 - 0 |