| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-04 | Clemson | 3 | 39.98 | 10 - 3 |
| 2021-09-11 | UAB | 83 | 94.55 | 56 - 7 |
| 2021-09-18 | South Carolina | 74 | 94.41 | 40 - 13 |
| 2021-09-25 | @ Vanderbilt | 122 | 96.99 | 62 - 0 |
| 2021-10-02 | Arkansas | 17 | 86.24 | 37 - 0 |
| 2021-10-09 | @ Auburn | 21 | 80.65 | 34 - 10 |
| 2021-10-16 | Kentucky | 33 | 92.29 | 30 - 13 |
| 2021-10-30 | Florida | 11 | 84.86 | 0 - 0 |
| 2021-11-06 | Missouri | 109 | 98.60 | 43 - 6 |
| 2021-11-13 | @ Tennessee | 25 | 85.36 | 41 - 17 |
| 2021-11-20 | Charleston So | 183 | 99.72 | 56 - 7 |
| 2021-11-27 | @ Georgia Tech | 104 | 96.70 | 45 - 0 |