| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-02 | LIU Post | 249 | 96.97 | 48 - 10 |
| 2021-09-11 | Texas St | 132 | 54.87 | 17 - 23 |
| 2021-09-18 | @ Texas Tech | 81 | 14.66 | 21 - 54 |
| 2021-09-25 | @ C Michigan | 98 | 17.92 | 27 - 31 |
| 2021-10-02 | @ FL Atlantic | 90 | 17.83 | 21 - 58 |
| 2021-10-08 | Charlotte | 118 | 40.04 | 33 - 45 |
| 2021-10-23 | WKU | 80 | 20.27 | 19 - 34 |
| 2021-10-30 | @ Marshall | 62 | 8.13 | 0 - 38 |
| 2021-11-06 | Old Dominion | 138 | 36.94 | 24 - 47 |
| 2021-11-13 | @ MTSU | 97 | 10.21 | 10 - 50 |
| 2021-11-20 | North Texas | 136 | 20.93 | 7 - 49 |
| 2021-11-27 | @ Southern Miss | 160 | 14.81 | 17 - 37 |