| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-04 | FL Atlantic | 90 | 92.17 | 35 - 14 |
| 2021-09-11 | @ South Florida | 133 | 94.67 | 42 - 20 |
| 2021-09-18 | Alabama | 1 | 14.66 | 29 - 31 |
| 2021-09-25 | Tennessee | 54 | 83.44 | 38 - 14 |
| 2021-10-02 | @ Kentucky | 53 | 75.87 | 13 - 20 |
| 2021-10-09 | Vanderbilt | 160 | 97.13 | 42 - 0 |
| 2021-10-16 | @ LSU | 37 | 61.68 | 42 - 49 |
| 2021-10-30 | Georgia | 2 | 15.14 | 0 - 0 |
| 2021-11-06 | @ South Carolina | 106 | 83.07 | 17 - 40 |
| 2021-11-13 | Samford | 174 | 95.18 | 70 - 52 |
| 2021-11-20 | @ Missouri | 101 | 66.65 | 23 - 24 |
| 2021-11-27 | Florida St | 53 | 55.15 | 24 - 21 |