| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-02 | Incarnate Word | 192 | 77.43 | 44 - 41 |
| 2021-09-11 | @ Michigan St | 49 | 6.30 | 14 - 42 |
| 2021-09-25 | W Illinois | 177 | 66.84 | 35 - 38 |
| 2021-10-02 | @ Northern Iowa | 99 | 14.32 | 7 - 34 |
| 2021-10-09 | Missouri St | 124 | 32.71 | 41 - 33 |
| 2021-10-23 | @ Indiana St | 193 | 53.96 | 17 - 28 |
| 2021-10-30 | S Dakota St | 67 | 13.76 | 16 - 47 |
| 2021-11-06 | @ North Dakota | 102 | 13.76 | 21 - 24 |
| 2021-11-13 | N Dakota St | 53 | 12.14 | 17 - 49 |
| 2021-11-20 | @ S Illinois | 96 | 12.79 | 35 - 18 |