| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-02 | @ Ball St | 61 | 3.93 | 21 - 31 |
| 2021-09-11 | @ Montana | 81 | 8.10 | 7 - 42 |
| 2021-09-18 | E Washington | 116 | 26.48 | 56 - 62 |
| 2021-09-25 | @ Youngstown St | 154 | 33.16 | 38 - 35 |
| 2021-10-02 | S Illinois | 103 | 21.26 | 30 - 31 |
| 2021-10-09 | @ Indiana St | 187 | 51.30 | 27 - 37 |
| 2021-10-16 | S Dakota St | 59 | 11.15 | 17 - 41 |
| 2021-10-23 | @ North Dakota | 116 | 18.75 | 10 - 34 |
| 2021-10-30 | Illinois St | 148 | 42.85 | 38 - 31 |
| 2021-11-06 | South Dakota | 111 | 28.22 | 21 - 42 |
| 2021-11-20 | @ Northern Iowa | 95 | 11.51 | 3 - 41 |