| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-02 | Bowling Green | 215 | 98.49 | 38 - 6 |
| 2021-09-11 | Pittsburgh | 38 | 51.13 | 34 - 41 |
| 2021-09-18 | Tennessee Tech | 225 | 98.56 | 56 - 0 |
| 2021-09-25 | @ Florida | 11 | 16.56 | 14 - 38 |
| 2021-10-02 | @ Missouri | 57 | 42.70 | 62 - 24 |
| 2021-10-09 | South Carolina | 81 | 75.94 | 45 - 20 |
| 2021-10-16 | Mississippi | 14 | 43.15 | 26 - 31 |
| 2021-10-23 | @ Alabama | 1 | 7.21 | 24 - 52 |
| 2021-11-06 | @ Kentucky | 33 | 46.64 | 45 - 42 |
| 2021-11-13 | Georgia | 1 | 14.64 | 17 - 41 |
| 2021-11-20 | South Alabama | 129 | 90.36 | 60 - 14 |
| 2021-11-27 | Vanderbilt | 143 | 95.22 | 45 - 21 |