| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-04 | Monmouth NJ | 132 | 58.05 | 50 - 15 |
| 2021-09-11 | @ Virginia Tech | 41 | 14.20 | 14 - 35 |
| 2021-09-18 | @ UT San Antonio | 87 | 26.69 | 13 - 27 |
| 2021-09-24 | @ Charlotte | 117 | 46.19 | 39 - 42 |
| 2021-10-02 | Marshall | 70 | 29.84 | 34 - 28 |
| 2021-10-09 | @ Liberty | 33 | 15.71 | 13 - 41 |
| 2021-10-22 | @ Connecticut | 191 | 76.48 | 44 - 13 |
| 2021-10-30 | Southern Miss | 184 | 89.93 | 35 - 10 |
| 2021-11-06 | @ WKU | 63 | 28.50 | 21 - 48 |
| 2021-11-13 | Florida Intl | 186 | 89.79 | 50 - 10 |
| 2021-11-20 | Old Dominion | 112 | 67.66 | 17 - 24 |
| 2021-11-27 | @ FL Atlantic | 126 | 54.92 | 27 - 17 |