| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-04 | @ Oklahoma St | 22 | 2.43 | 16 - 23 |
| 2021-09-11 | Cent Arkansas | 150 | 61.70 | 43 - 34 |
| 2021-09-25 | South Dakota | 125 | 49.06 | 31 - 23 |
| 2021-10-02 | @ Illinois St | 149 | 51.45 | 41 - 20 |
| 2021-10-09 | @ Youngstown St | 179 | 67.29 | 33 - 41 |
| 2021-10-16 | Indiana St | 180 | 74.19 | 37 - 7 |
| 2021-10-23 | @ N Dakota St | 61 | 16.45 | 20 - 27 |
| 2021-10-30 | North Dakota | 105 | 59.65 | 32 - 28 |
| 2021-11-06 | @ S Illinois | 92 | 38.65 | 38 - 28 |
| 2021-11-13 | Northern Iowa | 85 | 61.17 | 34 - 27 |
| 2021-11-20 | @ Dixie St | 237 | 95.71 | 55 - 24 |