| Date | Opponent | Rank | Win % | Score |
|---|---|---|---|---|
| 2021-09-04 | @ Pittsburgh | 39 | 1.55 | 7 - 51 |
| 2021-09-11 | Boston College | 53 | 3.48 | 28 - 45 |
| 2021-09-18 | E Michigan | 112 | 15.65 | 28 - 42 |
| 2021-09-25 | @ Coastal Car | 42 | 2.54 | 3 - 53 |
| 2021-10-02 | Toledo | 89 | 8.45 | 7 - 45 |
| 2021-10-09 | Connecticut | 186 | 37.23 | 27 - 13 |
| 2021-10-23 | @ Florida St | 81 | 4.90 | 3 - 59 |
| 2021-10-30 | @ Liberty | 58 | 2.27 | 17 - 62 |
| 2021-11-06 | Rhode Island | 209 | 45.56 | 22 - 35 |
| 2021-11-13 | Maine | 176 | 26.83 | 10 - 35 |
| 2021-11-20 | @ Army | 66 | 1.53 | 17 - 33 |
| 2021-11-27 | @ New Mexico St | 181 | 21.70 | 27 - 44 |